We discovered that IL-1 strongly increased the manifestation of tryptophane hydroxylase (TH), the enzyme in charge of 5-HT synthesis. in iNOS manifestation and remarkably with an upregulation of tryptophane hydroxylase and proteins Kinase C in membrane lipid rafts recommending that compensatory systems develop to counteract IL-1 inhibitory results. We also demonstrate that disruption of membrane … Continue reading We discovered that IL-1 strongly increased the manifestation of tryptophane hydroxylase (TH), the enzyme in charge of 5-HT synthesis